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    200 ml bottle of Alpecin Caffeine DMG Shampoo
    Split image: On the left side, there's a red hair root with the note "DMG promotes micro-circulation"; on the right side, a blue hair root is shown with the note "Caffeine stimulates the hair root"
    200 ml bottle of Alpecin Caffeine DMG Shampoo; next to it is the text "Caffeine + DMG: Studies show: Reduces hereditary hair loss, May boost hair growth"
    200 ml bottle of Alpecin Caffeine DMG Shampoo; next to it are a calendar icon with the heading "Use daily" and a stopwatch icon with the heading "Leave on for 2 minutes"
    Back of a 200 ml bottle of Alpecin Caffeine DMG Shampoo
    Three 200 ml bottles of Alpecin Caffeine DMG Shampoo are standing side by side.
    Two 200 ml bottles of Alpecin Caffeine DMG Shampoo and one 200 ml bottle of Alpecin Caffeine DMG Serum are standing side by side

    Alpecin

    Caffeine DMG Shampoo

    4 / 5 (100)

    Active complex of caffeine + DMG (dimethylglycine)

    • Effectively reduces hereditary hair loss
    • Can increase hair growth**
    • Important: Leave on for 2 minutes
    • Only available here in the Alpecin Shop
    11 % DiscountOld price: €65.97New price: €58.99600 ml (€98.32 / 1 l) • including VAT, plus shipping

    Delivery options

    For daily use, we recommend 200 ml per month.

    available

    Average delivery time: 4-6 days. The exact delivery time will be calculated at checkout.

    Free shipping on orders over 45 €

    Aqua, Sodium Laureth Sulfate, Laureth-2, Citric Acid, Disodium Laureth Sulfosuccinate, Sodium Lauroyl Glutamate, Sodium Dimethylglycinate, Caffeine, Panthenol, PEG-120 Methyl Glucose Dioleate, Sodium Chloride, Sodium Citrate, Propylene Glycol, Menthol, PEG-40 Hydrogenated Castor Oil, Polyquaternium-7, Disodium EDTA, Zinc PCA, Niacinamide, Sodium Benzoate, Potassium Sorbate, Parfum, CI 42090.

    • Free shipping on orders over 45 €

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            © 2026 DR. KURT WOLFF GMBH & CO. KG
            Effectiveness depends on individual metabolism. 74% of study participants noticed thicker, denser, and fuller-looking hair after 6 months of use.
            ESzW

            Dr. Erik Schulze zur Wiesche

            Head of Research & Development

            FAQFAQ: Answers to your questions

            Already after 3 months of regular use, clinical studies have shown a significant reduction in hereditary hair loss.

            As a scientifically oriented company, Dr. Wolff places the highest value on sound research and evidence-based statements. We are currently a pioneer in the field of topical application of N,N-dimethylglycine (DMG). To generate valid and objective data, we rely on a high-quality study design. Our investigations – for example into the Alpecin Caffeine-DMG products – were therefore conducted in a placebo-controlled, randomised, and double-blind manner. A brief explanation of these terms:

            • Placebo-controlled: One group receives the active ingredient formulation, another receives a placebo. This allows the actual effectiveness to be assessed objectively.
            • Randomised: Allocation to the groups is made at random in order to avoid systematic bias.
            • Double-blind: Neither the study participants nor the technical staff know who is receiving which treatment, ensuring unbiased results.

            For a successful anti-hair loss routine, daily and consistent use is highly recommended. Please note the required exposure time of 2 minutes.

            Unlike medicinal products, no undesirable side effects are to be expected with regular use. None were found in studies or reported by consumers so far.

            Microscopic image of the smallest blood vessels surrounding the left part of a hair root, symbolising the effect of DMG on the micro-circulation of the scalp and its impact against hereditary hair loss in men.

            Mode of actionMode of action: DMG promotes the micro-blood-circulation of the scalp

            Hair loss* is effectively reduced.

            Microscopic image of the smallest blood vessels surrounding the right part of a hair root, symbolising the effect of DMG on the micro-circulation of the scalp and its impact against hereditary hair loss in men.

            Micro-blood-circulation: The foundation for healthy hair growth

            In areas affected by hair loss, this is reduced to below 40 %.

            This is where DMG comes in:
            Its mode of action, comparable to Minoxidil, ensures improved micro-blood-circulation and the hair roots are once again supplied with nutrients.

            Microscopic image of a hair root in brown and blue, intended to symbolise the effect of the Alpecin Caffeine Complex

            Additionally, caffeine stimulates the hair root

            Part two of a tripartite depiction showing a microscopic view of a hair root.

            Caffeine + DMG: Even more effective when combined

            Micro-circulation of the scalp

            A circular heatmap of a head, predominantly in blue with a small central yellow and red area, shows intensity variations of micro-circulation against a dark blue background.

            BEFORE application:

            A circular heatmap of a head with vibrant red, yellow, and blue tones shows intensity variations of micro-circulation against a dark blue background.

            AFTER application:

            Measurement of micro-circulation before and after using Alpecin Caffeine DMG Shampoo (Vertical head shot with a special laser camera for measuring blood flow).

            A bird's-eye view image of a male head with a grid displayed on it, illustrating that a large portion of the hairs of the study participants were examined.

            Measurement methodMeasurement method: First-time evaluation of more than 10.000 individual hairs

            Focus on a screen displaying a close-up of scalp hair, illustrating that Dr. Wolff, in collaboration with the Fraunhofer Institute, has developed a new method to analyse hereditary hair loss in men.

            In collaboration with the Fraunhofer Institute, Dr. Wolff Research has now taken a systemic approach to hair loss* and conducted a comprehensive analysis of the human scalp.

            Whereas previous studies examined areas with only around 300 hairs, our new method, which evaluates more than 10.000 hairs per head, provides precise results:

            The combination of caffeine and DMG can effectively reduce hair loss*. And in some cases, new hair growth** was even observed.

            Clinical StudyClinical Study: Reduction in hair loss* demonstrated in 92% of participants

            The graph shows the results of the hair pull test over time, comparing "Caffeine + DMG" with "Placebo." The test group decreases, while the control group increases. The X-axis marks the days, and the Y-axis shows the mean values with confidence intervals.

            Double-blind, randomised, and placebo-controlled study:

            The clinical study was conducted on 154 men with hereditary hair loss. These men used either the new Caffeine DMG Shampoo (verum) or a placebo shampoo over a period of 6 months.

            Hair growth** can be increased

            Three close-up shots of skin show hair growth at intervals: "Day 0," "Day 84," and "Day 168." Each image displays different hair density on a similar skin surface.
            Phototrichogram: Clinical tests conducted at Eurofins Cosmetics & Personal Care Italy.

            The analysis of the study subgroup showed a significant increase in hair growth**:

            Read the full study

            ApplicationApplication: This is the only way to achieve the best result

            Also available as a serum

            VideoVideo: The Alpecin Story

            You might also like:

            * hereditary hair loss
            ** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss

            Your chance for more: Get expert hair care advice and be among the first to learn about new Alpecin products.

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            NewNew: Caffeine DMG Serum

            Highly effective serum with caffeine + DMG (dimethylglycine)

            • Effectively reduces hereditary hair loss
            • May boost hair growth**
            • Leave-in product
            • Important: Massage in and do not rinse out
            Discover the serum

            Or as a bundle

            Our bundle consists of 2x shampoo and 1x serum and is the perfect combination to ensure your daily dose of Caffeine DMG.

            Discover the bundle

            • Apply daily

            • Leave on for 2 minutes

            • Use continuously

            • Tip for your daily dose of Caffeine DMG
              Use the Caffeine DMG Serum on no-wash days!

            You can easily combine the Caffeine DMG Shampoo and the Caffeine DMG Serum, but it's not absolutely necessary to use both products at the same time.

            What's crucial is that your hair and scalp receive a daily dose of Caffeine DMG.

            We recommend using the shampoo on days when you wash your hair and the serum on days when you don't.

            No, the effectiveness of Alpecin Caffeine DMG Shampoo is primarily focused on the hair roots and is independent of hair length. Depending on the hair length, additional hair care should be applied.

            To the general FAQs

            Caffeine has been known for over 20 years for its growth-stimulating effect on hair roots. It inhibits the breakdown of the intracellular messenger cAMP. This provides cells with more energy and stimulates cell growth.

            Caffeine is thus the most researched plant-based active ingredient against hereditary hair loss.

            Individually, caffeine and DMG are already highly potent active ingredients. In Alpecin's unique, patented active complex, they are now even more powerful.

            The result: Hereditary hair loss is now effectively reduced and hair growth** can be increased.

            The OMR Original takes a behind-the-scenes look at Alpecin and reveals how a chance discovery in the lab, bold decisions, ambitious goals, and unconventional marketing have paved the way for Alpecin to become the leading – and often copied – manufacturer of hair loss* products.

            View the full story
            200 ml bottle of Alpecin Caffeine DMG Serum​

            Caffeine DMG Serum

            Single Pack

            4 / 5 (32)
            €32.99200 ml (€164.95 / 1 l) • including VAT, plus shipping
            Two 200 ml bottles of Alpecin Caffeine DMG Shampoo and one 200 ml bottle of Alpecin Caffeine DMG Serum are standing side by side

            Caffeine DMG Shampoo + Serum

            Multi-Pack

            4.5 / 5 (28)
            10 % DiscountOld price: €76.97New price: €68.99600 ml (€114.98 / 1 l) • including VAT, plus shipping
            200 ml bottle of Alpecin Grey Attack MAX Caffeine & Colour Shampoo; next to the cap is a yellow notice with the words "Optimised Formulation"

            Grey Attack MAX

            Single Pack

            4 / 5 (49)
            €26.99200 ml (€134.95 / 1 l) • including VAT, plus shipping