Free shipping on orders over 45 €

Alpecin Logo

Caffeine DMG against hereditary hair loss

Discover how DMG and caffeine can reduce male pattern hair loss and promote hair growth**

Learn more about DMG

DMG: Breakthrough in Hair Loss* Research

Dimethylglycine (DMG) promotes microcirculation in the scalp, ensuring the hair roots are supplied with nutrients again.

Thanks to decades of research, it's known that caffeine boosts hair root activity and extends the growth phase of hair roots.

The new active ingredient, Dimethylglycine (DMG), was previously completely unknown in dermatological research. Studies show that DMG increases microcirculation, meaning it enhances the blood supply to the smallest blood vessels, thereby improving the nutrient supply to the hair roots.

Microscopic image of a hair root, with the smallest blood vessels surrounding the hair follicle highlighted in red, symbolising that DMG enhances microcirculation
Blood supply to the smallest blood vessels (microcirculation)
Nutrient supply to the hair root

Microcirculation: the foundation for healthy hair growth

Caffeine and DMG support the nutrient supply and activity of the hair roots. These two effects are particularly important when the hair follicle is weakened.

A clinical study shows that the patented combination of caffeine and DMG effectively reduces hereditary hair loss and can even increase hair growth**.

Schematic Representation of the Dilation of the Smallest Blood Vessels in the Hair Root as a Symbol of DMG's Effect Against Hereditary Hair Loss in Men
Schematic Representation of Vessel Dilation After DMG Addition
Clinical study

A reduction in hair loss was observed in 92% of the participants*

Double-blind, randomised, and placebo-controlled study:

The graph shows the results of the hair pull test over time, comparing "Caffeine + DMG" with "Placebo." The test group decreases, while the control group increases. The X-axis marks the days, and the Y-axis shows the mean values with confidence intervals.

The clinical study was conducted on 154 men with hereditary hair loss. These men used either the new Caffeine DMG shampoo (Verum) or a placebo shampoo over a period of 6 months.

Hair growth** can be increased

The analysis of the study subgroup showed a significant increase in hair growth**:

Three close-up shots of skin show hair growth at intervals: "Day 0," "Day 84," and "Day 168." Each image displays different hair density on a similar skin surface.
Phototrichogram: Clinical tests conducted at Eurofins Cosmetics & Personal Care Italy.
Dimethylglycine (DMG): A substance that naturally occurs in all body cells and plays a key role in cellular metabolism.ESzW

Dr. Erik Schulze zur Wiesche

Head of Research & Development

Video

The Alpecin Story

The OMR Original takes a behind-the-scenes look at Alpecin and reveals how a chance discovery in the lab, bold decisions, ambitious goals, and unconventional marketing have paved the way for Alpecin to become the leading – and often copied – manufacturer of hair loss* products.

* hereditary hair loss
** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss