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200 ml bottle of Alpecin Caffeine DMG Serum​
Split image: On the left side, there's a red hair root with the note "DMG promotes micro-circulation"; on the right side, a blue hair root is shown with the note "Caffeine stimulates the hair root"
200 ml bottle of Alpecin Caffeine DMG Serum; next to it are a calendar icon with the heading "Use daily" and an icon of a crossed-out shower with the heading "Do not rinse out"
Back of a 200 ml bottle of Alpecin Caffeine DMG Serum
Two 200 ml bottles of Alpecin Caffeine DMG Serum are standing side by side
Two 200 ml bottles of Alpecin Caffeine DMG Shampoo and one 200 ml bottle of Alpecin Caffeine DMG Serum are standing side by side
NEW

Caffeine DMG Serum

Highly effective serum with caffeine + DMG (dimethylglycine)

  • Effectively reduces hereditary hair loss
  • Can increase hair growth**
  • Important: Massage into the scalp and do not rinse
  • Only available here in the Alpecin Shop
10 % Discount
Old price: 65,98 €New price: 58,99 €400 ml (147,47 € / 1 l) • including VAT, plus shipping

Delivery options

  • available
  • Average delivery time: 4-6 days. The exact delivery time will be calculated at checkout.
  • Free shipping on orders over €45
Aqua, Alcohol Denat., Citric Acid, Sodium Dimethylglycinate, PEG-40 Hydrogenated Castor Oil, Panthenol, Menthol, Caffeine, Zinc PCA, Niacinamide, Parfum.
Avoid contact with eyes.
Mode of action

DMG promotes the micro-blood-circulation of the scalp

Hair loss* is effectively reduced.

Micro-blood-circulation: The foundation for healthy hair growth

In areas affected by hair loss, this is reduced to below 40 %.

This is where DMG comes in:
Its mode of action, comparable to Minoxidil, ensures improved micro-blood-circulation and the hair roots are once again supplied with nutrients.

Additionally, caffeine stimulates the hair root

Caffeine has been known for over 20 years for its growth-stimulating effect on hair roots. It inhibits the breakdown of the intracellular messenger cAMP. This provides cells with more energy and stimulates cell growth.

Caffeine is thus the most researched plant-based active ingredient against hereditary hair loss.

Caffeine + DMG: Even more effective when combined

Individually, caffeine and DMG are already highly potent active ingredients. In Alpecin's unique, patent-pending complex, they are now even more powerful.

The result: Hereditary hair loss is now effectively reduced, and hair growth** can be increased.

The new Caffeine DMG Serum is Alpecin's strongest product against hair loss.ESzW

Dr. Erik Schulze zur Wiesche

Head of Research & Development

Application

This is the only way to achieve the best result

Apply daily

Massage in and do not rinse out

Use consistently

Also available as a shampoo

Alpecin Caffeine DMG Shampoo: One bottle of Caffeine DMG Shampoo is standing on a white, slightly wavy surface

Caffeine DMG Shampoo

Effective anti-hair loss* shampoo with caffeine + DMG (dimethylglycine)

  • Effectively reduces hereditary hair loss
  • May boost hair growth**
  • Important: Leave on for 2 minutes
Alpecin Caffeine DMG Bundle: Two bottles of Caffeine DMG Shampoo and one bottle of Caffeine DMG Serum are standing side by side on a white, slightly wavy surface

Or as a bundle

Our bundle consists of 2x shampoo and 1x serum and is the perfect combination to ensure your daily dose of Caffeine DMG.

No time to wash your hair? Use our serum on no-wash days.

Measurement method

First-time evaluation of more than 100.000 individual hairs

In collaboration with the Fraunhofer Institute, Dr. Wolff Research has now taken a systemic approach to hair loss* and conducted a comprehensive analysis of the human scalp.

Whereas previous studies examined areas with only around 300 hairs, our new method, which evaluates more than 10.000 hairs per head, provides precise results:

The combination of caffeine and DMG can effectively reduce hair loss*. And in some cases, new hair growth** was even observed.

Clinical study

Hair loss* was reduced in 94% of participants

Double-blind, randomised, and placebo-controlled study:

The graph shows the results of the hair pull test over time, comparing "Caffeine + DMG" with "Placebo." The test group decreases, while the control group increases. The X-axis marks the days, and the Y-axis shows the mean values with confidence intervals.

The clinical study was conducted on 154 men with hereditary hair loss. These men used either the new Caffeine DMG Serum (verum) or a placebo serum over a period of 6 months.

Hair growth** can be increased

The analysis of the study subgroup showed a significant increase in hair growth**:

Three close-up shots of skin show hair growth at intervals: "Day 0," "Day 84," and "Day 168." Each image displays different hair density on a similar skin surface.
Phototrichogram: Clinical tests conducted at Eurofins Cosmetics & Personal Care Italy.
Video

The Alpecin Story

The OMR Original takes a behind-the-scenes look at Alpecin and reveals how a chance discovery in the lab, bold decisions, ambitious goals, and unconventional marketing have paved the way for Alpecin to become the leading – and often copied – manufacturer of hair loss* products.

FAQ

Answers to your questions

Already after 3 months of regular use, clinical studies have shown a significant reduction in hereditary hair loss.

As a scientifically oriented company, Dr. Wolff places the highest value on sound research and evidence-based statements. We are currently a pioneer in the field of topical application of N,N-dimethylglycine (DMG). To generate valid and objective data, we rely on a high-quality study design. Our investigations – for example into the Alpecin Caffeine-DMG products – were therefore conducted in a placebo-controlled, randomised, and double-blind manner. A brief explanation of these terms:

  • Placebo-controlled: One group receives the active ingredient formulation, another receives a placebo. This allows the actual effectiveness to be assessed objectively.
  • Randomised: Allocation to the groups is made at random in order to avoid systematic bias.
  • Double-blind: Neither the study participants nor the technical staff know who is receiving which treatment, ensuring unbiased results.

For a successful treatment of hereditary hair loss, it's essential to apply Caffeine DMG to the scalp daily. Important: Do not rinse out the serum.

* hereditary hair loss
** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss