Alpecin research: Innovative active ingredients
Our unique active ingredients and formulations are developed locally in Bielefeld, and their effectiveness is verified in internationally conducted studies!
Our research focuses on solutions for the most relevant hair problems. To achieve this, we continuously search for new, potent active ingredients and develop formulations optimised for men.
Dr Erik Schulze zur Wiesche
Head of Research and Development
¹ C. Bussoletti, F. Mastropietro, M. V. Tolaini, L. Celleno (2010): Use of a caffeine shampoo for the treatment of male androgenetic alopecia. Journal of Applied Cosmetology. 28,4 (Oct. 2010), 153-162.
² Dhurat R, Chitallia J, May TW, Jayaraaman AM, Madhukara J, Anandan S, Vaidya P, Klenk A. (2017): An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia. Skin Pharmacol Physiol. ;30(6):298-305.
³ Otberg N, Teichmann A, Rasuljev U, Sinkgraven R, Sterry W, Lademann J (2007): Follicular penetration of topically applied caffeine via a shampoo formulation. Skin Pharmacol Physiol.;20(4):195-8.
Caffeine has been known for more than 20 years for its growth-stimulating effect on hair roots. It inhibits the breakdown of the intracellular messenger cAMP. As a result, more energy is available to the cells and cell growth is stimulated.
Caffeine is therefore the most researched active ingredient of plant origin against hereditary hair loss.
Micro-circulation is the foundation for healthy hair growth.
In areas affected by hair loss*, this is reduced to below 40 %.
5,6-Dihydroxyindole, or 5,6-DHI for short, is a preliminary stage of the natural hair pigment melanin. When applied, 5,6-DHI binds directly to the hair, penetrates the hair shaft, and forms colour molecule chains in the hair with oxygen. The hair becomes darker.
* hereditary hair loss
** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss
Discover which Alpecin product suits you best - tailored individually for strong hair and a healthy scalp.
Alpecin Cycling provides amateur cyclists with tips on training, tactics, nutrition, equipment, and health related to road cycling and gravel riding.
Expert in hair loss, dandruff, dry scalp & grey hair
Innovative active ingredients and clinically proven effectiveness
Specifically developed for men and their needs
The OMR Original takes a look behind the scenes at Alpecin and shows how a chance discovery in the lab, the courage to make radical decisions, ambitious goals, and unconventional marketing paved the way for Alpecin to become the leading – and often copied – manufacturer of products against hair loss*.
