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A bottle of Alpecin Caffeine DMG Shampoo and a bottle of Alpecin Caffeine DMG Serum are standing upright on a smooth surface.A bottle of Alpecin Caffeine DMG Shampoo and a bottle of Alpecin Caffeine DMG Serum are standing upright on a smooth surface.

Our strongest doping for your hair

The new anti-hair loss* formula with caffeine + DMG

Discover now

The Alpecin brand: What sets us apart

  • Expert in hair loss, dandruff, dry scalp & grey hair

  • Innovative active ingredients and clinically proven effectiveness

  • Specifically developed for men and their needs

Product finder: Purely a matter of type: Find the ideal Alpecin for you

Discover which Alpecin product suits you best - tailored individually for strong hair and a healthy scalp.

Product categories: Discover our categories

New: Caffeine DMG Serum

Highly effective serum with Caffeine + DMG (Dimethylglycine)

  • Effectively reduces hereditary hair loss

  • Can boost hair growth**

  • Leave-In product

  • Important: Massage in and do not rinse out

Alpecin research: Innovative active ingredients

Our unique active ingredients and formulations are developed locally in Bielefeld, and their effectiveness is verified in internationally conducted studies!

Microscopic image of a hair root in brown and blue, intended to symbolise the effect of the Alpecin Caffeine Complex.

Caffeine stimulates the hair roots

Caffeine has been known for more than 20 years for its growth-stimulating effect on hair roots. It inhibits the breakdown of the intracellular messenger cAMP. As a result, more energy is available to the cells and cell growth is stimulated.

Caffeine is therefore the most researched active ingredient of plant origin against hereditary hair loss.

Microscopic image of the smallest blood vessels surrounding a hair root as a symbol of the effect of DMG on the microcirculation of the scalp and the effect against hereditary hair loss in men

DMG promotes the micro-blood-circulation of the scalp

Micro-circulation is the foundation for healthy hair growth.

In areas affected by hair loss*, this is reduced to below 40 %.

A black structural model against a white background represents the active ingredient 5,6-DHI in Alpecin Repigmentation Shampoos.

5,6-DHI repigments the hair

5,6-Dihydroxyindole, or 5,6-DHI for short, is a preliminary stage of the natural hair pigment melanin. When applied, 5,6-DHI binds directly to the hair, penetrates the hair shaft, and forms colour molecule chains in the hair with oxygen. The hair becomes darker.

Our research focuses on solutions for the most relevant hair problems. To achieve this, we continuously search for new, potent active ingredients and develop formulations optimised for men.
ESzW

Dr Erik Schulze zur Wiesche

Head of Research and Development

Proven effectiveness

  • Clinical study: Clinical efficacy study with innovative shampoo containing DMG and caffeine shows tremendous efficacy against hereditary hair loss

    Conducted at the Centre for Cosmetic Research, Catholic University Sacred Heart in Rome, Italy

  • Clinical study: Alpecin Caffeine Shampoo reduces hereditary hair loss¹

    Conducted at the Center for Cosmetic Research at Sacred Heart Catholic University in Rome, Italy

  • Clinical study: Alpecin Caffeine Liquid is just as effective against hereditary hair loss as medical treatment with minoxidil²

    Conducted at five research centers under the direction of Lokmanya Tilak Municipal General Hospital in Mumbai (India)

  • Clinical study: Caffeine shampoo can be detected in the hair follicle for 24 hours after just 2 minutes of application³

    Conducted at the Center for Experimental and Applied Skin Physiology and Clinical Research Center for Hair and Skin Physiology of the Charité University Hospital, Berlin

  • Further studies & research results

    Discover all studies

Video: The Alpecin Story

The OMR Original takes a look behind the scenes at Alpecin and shows how a chance discovery in the lab, the courage to make radical decisions, ambitious goals, and unconventional marketing paved the way for Alpecin to become the leading – and often copied – manufacturer of products against hair loss*.

* hereditary hair loss
** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss

¹ C. Bussoletti, F. Mastropietro, M. V. Tolaini, L. Celleno (2010): Use of a caffeine shampoo for the treatment of male androgenetic alopecia. Journal of Applied Cosmetology. 28,4 (Oct. 2010), 153-162.

² Dhurat R, Chitallia J, May TW, Jayaraaman AM, Madhukara J, Anandan S, Vaidya P, Klenk A. (2017): An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia. Skin Pharmacol Physiol. ;30(6):298-305.

³ Otberg N, Teichmann A, Rasuljev U, Sinkgraven R, Sterry W, Lademann J (2007): Follicular penetration of topically applied caffeine via a shampoo formulation. Skin Pharmacol Physiol.;20(4):195-8.

Cyclist wearing a helmet and Alpecin Cycling jersey rides a road bike through vineyardsCyclist wearing a helmet and Alpecin Cycling jersey rides a road bike through vineyards

Alpecin Cycling: The Cycling Magazine

Alpecin Cycling provides amateur cyclists with tips on training, tactics, nutrition, equipment, and health related to road cycling and gravel riding.

Go to Alpecin Cycling