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Alpecin Caffeine DMG Serum bottle; label reads “Enhances hair performance,” “Leave-in,” and “Patented formula: Ingredient complex of caffeine + dimethylglycine (DMG),” 200 mL.
Red bottle with label: “Caffeine + DMG Serum promotes natural hair growth,” key ingredients DMG and caffeine, application instructions, flammability warning, and ingredient list.
Two Alpecin Caffeine DMG Serum bottles, labeled “Enhances hair performance,” “Leave-in,” 200 mL.
Three Alpecin bottles: two Caffeine DMG Shampoo and one Caffeine DMG Serum, all labeled “Enhances hair performance,” 200 mL.

Over 125,000 bottles sold worldwide:

Alpecin

Caffeine DMG Serum

Patented formula: caffeine + dimethylglycine (DMG) complex

  • Effectively reduces hereditary hair loss
  • Can increase hair growth**
  • Important: Massage into the scalp and do not rinse
  • Only available in the Alpecin Shop
10 % DiscountOld price: $89.90New price: $80.99400 mL ($20.25 / 100 mL) • excluding taxes, plus shipping

Delivery Options

IMPORTANT: Daily use is recommended for 3 months to see visible results.

available

Delivery time: 2-4 business days

Free shipping on orders over $50

Water, Alcohol, Citric Acid, Sodium Dimethylglycinate, PEG-40 Hydrogenated Castor Oil, Panthenol, Menthol, Caffeine, Zinc PCA, Niacinamide, Fragrance.

Product is flammable. Keep out of reach of children. Use only as directed. For external use only. Avoid contact with eyes. If contact occurs, rinse with water. In the unlikely event of skin irritation, discontinue use.

Microscopic image of the smallest blood vessels surrounding the left part of a hair root, symbolising the effect of DMG on the micro-circulation of the scalp and its impact against hereditary hair loss in men.

Mode of Action: DMG Promotes the Micro-Circulation of the Scalp

Hair loss* is effectively reduced.

Microscopic image of the smallest blood vessels surrounding the right part of a hair root, symbolising the effect of DMG on the micro-circulation of the scalp and its impact against hereditary hair loss in men.

Micro-Circulation: The Foundation for Healthy Hair Growth

In areas affected by hair loss, this is reduced to below 40 %.

This is where DMG comes in:
Its mode of action, comparable to Minoxidil, ensures improved micro-blood-circulation and the hair roots are once again supplied with nutrients.

Microscopic image of a hair root in brown and blue, intended to symbolise the effect of the Alpecin Caffeine Complex

Caffeine Stimulates the Hair Root

Caffeine has been known for over 20 years for its growth-stimulating effect on hair roots. It inhibits the breakdown of the intracellular messenger cAMP. This provides cells with more energy and stimulates cell growth.

Caffeine is thus the most researched plant-based active ingredient against hereditary hair loss.

Part two of a split depiction of a microscopic view of a hair root

Caffeine + DMG: Even More Effective Together

Individually, caffeine and DMG are already highly potent active ingredients. In Alpecin's unique, patented complex, they are now even more powerful.

The result: Hereditary hair loss is now effectively reduced, and hair growth** can be increased.

The new Caffeine DMG Serum is Alpecin's strongest product against hair loss.
ESzW

Dr. Erik Schulze zur Wiesche

Head of Research & Development

Application: This is the only way to achieve the best result

  • Apply daily

  • Massage in and do not rinse out

  • Use consistently for at least 3 months

Also available as a shampoo

Caffeine DMG Shampoo

Effective anti-hair loss* shampoo with caffeine + DMG (dimethylglycine)

  • Effectively reduces hereditary hair loss
  • May boost hair growth**
  • Important: Leave on for 2 minutes

Or as a bundle

Our bundle consists of 2x shampoo and 1x serum and is the perfect combination to ensure your daily dose of DMG.

No time to wash your hair? Use our serum on no-wash days.

A bird's-eye view image of a male head with a grid displayed on it, illustrating that a large portion of the hairs of the study participants were examined.

Measurement Method: First-time evaluation of more than 10,000 individual hairs

Focus on a screen displaying a close-up of scalp hair, illustrating that Dr. Wolff, in collaboration with the Fraunhofer Institute, has developed a new method to analyse hereditary hair loss in men.

In collaboration with the Fraunhofer Institute, Dr. Wolff Research has now taken a systemic approach to hair loss* and conducted a comprehensive analysis of the human scalp.

Previous studies examined areas with only around 300 hairs, our new method, which evaluates more than 10,000 hairs per head, provides precise results:

The combination of caffeine and DMG can effectively reduce hair loss*. In some cases, new hair growth** was observed.

Clinical study: Hair loss* was reduced in 94% of participants

The graph shows the results of the hair pull test over time, comparing "Caffeine + DMG" with "Placebo." The test group decreases, while the control group increases. The X-axis marks the days, and the Y-axis shows the mean values with confidence intervals.

Double-blind, randomized, and placebo-controlled study:

The clinical study was conducted on 154 men with hereditary hair loss. These men used either the new Caffeine DMG Serum (verum) or a placebo serum over a period of 6 months.

Increased Hair Growth**

Three close-up shots of skin show hair growth at intervals: "Day 0," "Day 84," and "Day 168." Each image displays different hair density on a similar skin surface.
Phototrichogram: Clinical tests conducted at Eurofins Cosmetics & Personal Care Italy.

The analysis of the study subgroup showed a significant increase in hair growth**:

Read the full study

Video: The Alpecin Story

Go behind the scenes at Alpecin and discover how a chance discovery in the lab, bold decisions, ambitious goals, and unconventional marketing have paved the way for Alpecin to become the leading – and often copied – manufacturer of hair loss* products.

FAQ: Answers to Your Questions

After just 3 months of regular use, clinical studies have shown a significant reduction in hereditary hair loss.

Dr. Wolff places the highest value on sound research and evidence-based statements. We are currently a pioneer in the field of topical application of N,N-dimethylglycine (DMG). To generate valid and objective data, we rely on a high-quality study design. Our investigations – for example into the Alpecin Caffeine-DMG products – were therefore conducted in a placebo-controlled, randomized, and double-blind manner. A brief explanation of these terms:

  • Placebo-controlled: One group receives the active ingredient formulation, another receives a placebo. This allows the actual effectiveness to be assessed objectively.
  • Randomized: Allocation to the groups is made at random in order to avoid systematic bias.
  • Double-blind: Neither the study participants nor the technical staff know who is receiving which treatment, ensuring unbiased results.

For a successful treatment of hereditary hair loss, it's essential to apply Caffeine DMG to the scalp daily. Important: Do not rinse out the serum.

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Alpecin Caffeine DMG Shampoo bottle; label reads “Enhances hair performance,” “Patented formula: Ingredient complex of caffeine + dimethylglycine (DMG),” 200 mL.

Caffeine DMG Shampoo

1-Month-Supply

$34.99200 mL ($17.50 / 100 mL) • excluding taxes, plus shipping
Three Alpecin bottles: two Caffeine DMG Shampoo and one Caffeine DMG Serum, all labeled “Enhances hair performance,” 200 mL.

Caffeine DMG Shampoo + Serum

DMG Growth Kit

15 % DiscountOld price: $114.97New price: $97.99600 mL ($16.33 / 100 mL) • excluding taxes, plus shipping

* hereditary hair loss
** in vivo study, subgroup analysis, placebo-controlled, n=30 participants with hereditary hair loss