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Microscopic image of the smallest blood vessels surrounding a hair root, symbolizing the effect of DMG on the microcirculation of the scalp and its impact against hereditary hair loss in men.Microscopic image of the smallest blood vessels surrounding a hair root, symbolizing the effect of DMG on the microcirculation of the scalp and its impact against hereditary hair loss in men.

DMG: Turning point in hair loss* research

Dimethylglycine (DMG) promotes microcirculation in the scalp, ensuring the hair roots are supplied with nutrients again.

Summary

Microscopic close-up of a hair root surrounded by blood vessels, symbolizing the importance of blood circulation in hereditary hair loss in men.
Blood supply to the smallest blood vessels (microcirculation)

Thanks to decades of research, it's known that caffeine boosts hair root activity and extends the growth phase of hair roots.

The new active ingredient, Dimethylglycine (DMG), was previously completely unknown in dermatological research. Studies show that DMG increases microcirculation, meaning it enhances the blood supply to the smallest blood vessels, thereby improving the nutrient supply to the hair roots.

Nutrient supply to the hair root: Microcirculation: the foundation for healthy hair growth

Schematic illustration of the dilation of the smallest blood vessels around the hair root, symbolizing the effect of DMG against hereditary hair loss in men.
Schematic Representation of Vessel Dilation After DMG Addition

Caffeine and DMG support the nutrient supply and activity of the hair roots. These two effects are particularly important when the hair follicle is weakened.

A clinical study shows that the patented combination of caffeine and DMG effectively reduces hereditary hair loss and can even increase hair growth**.

  • Clinical study: 92 %

    of users had a clinically proven reduction in hair loss***

    A double-blind, randomized, placebo-controlled study involving 154 men with hereditary hair loss, who used either the new Caffeine + DMG shampoo or a placebo shampoo daily over a period of 6 months.

Hair growth* can be increased

Three close-up shots of skin show hair growth at intervals: 'Day 0,' 'Day 84,' and 'Day 168.' Each image displays different hair density on a similar skin surface.
Phototrichogram: Clinical tests conducted at Eurofins Cosmetics & Personal Care Italy.

The analysis of the study subgroup showed a significant increase in hair growth**:

Read full study
Dimethylglycine (DMG): A substance that naturally occurs in all body cells and plays a key role in cellular metabolism.
ESzW

Dr. Erik Schulze zur Wiesche

Head of Research & Development

Video: The Alpecin Story

The OMR Original takes a look behind the scenes at Alpecin and shows how a chance discovery in the lab, the courage to make radical decisions, ambitious goals, and unconventional marketing paved the way for Alpecin to become the leading – and often copied – expert in caffeine-based hair care.

Guide: Recommended for You

  • A cross-sectional view of a hair follicle, highlighted in shades of brown and blue. Black arrows indicate specific dark regions within the follicle, suggesting areas of interest or focus for analysis.

    Why caffeine against hereditary hair loss?

    Caffeine stimulates the metabolism and is consumed globally. Find out more about the power of the active ingredient caffeine, how it strengthens your hair, and how it reduces hereditary hair loss.

  • A young man looks critically into the mirror to identify the first signs of hereditary hair loss

    Help with hereditary hair loss

    Find out how you can effectively counteract hereditary hair loss - without the use of medication!

  • A young man stands in front of a mirror, examining his receding hairline as a symbol of the question "How much hair loss is normal?"

    How much hair loss is normal?

    Are you wondering whether your hair loss is within the normal range? Find out what is considered normal and at what point you should take a closer look!

Caffeine DMG Shampoo

Ingredient complex of Caffeine + DMG (dimethylglycine)

  • Reduces hair loss* 
  • Supports hair growth*
  • Thicker, fuller & denser hair* 
  • Use daily & leave on for 2 minutes 
  • Optimal results after 3-6 months of daily use*

* hereditary hair loss
** in vivo study, n=15 participants with hereditary hair loss
*** 24-week RCT in men (n=154; daily use): standardised testing showed fewer hairs shed vs placebo at weeks 12 and 24; subgroup and consumer findings support higher density/growth-phase hairs and fuller-looking hair at 6 months. Hair loss not related to illness. Results vary.